4-chloropyrropyrimidine is an important pharmaceutical intermediate that is used, for example, as an intermediate for the treatment of tofacitinib in adult patients with moderate to severe rheumatoid joint chemicalitis with inadequate or intolerant methotrexate response. 4-chloropyrropyrimidine is also an important raw material for the development of many antibacterial, anti-tumor, anti-vertebrate and other drugs.